Basics of Cell Line Authentication and Where to Get it
Cell line authentication is a vital research tool. It is essential in fields like medicine, cell biology, genetics, vaccine development, etc. STR (short tandem repeat) profiling is the preferred method for human cell line authentication . The STR analysis helps in detecting misidentified and cross-contaminated cells in a cell line. In addition, the technique compares multiple STR markers between multiple cellular genomes. Why is Cell Line Authentication required? Tissue culture cells are crucial for scientific research in many laboratories. However, many of these cells are misidentified or contaminated with other cells. Thus, cell line authentication is important to save the loss of money and time due to such misidentified or cross-contaminated cell lines. The process is now recommended by the National Institutes of Health and many journals. Cell Line Authentication is typically done: • Before startin...